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Carbonyl Scavenger
Carbonyl Scavenger
Cytoprotective mechanisms of Carbonyl scavenging drugs in isolated rat hepatocytes
Carbonyl –scavenging drugs & protection against Carbonyl stress-associated cell injury.
Therapeutic potential of Carbonyl –scavenging carnosine derivative in metabolic disorders
High throughput assay for evaluation of reactive Carbonyl scavenging capacity
Edaravone inhibits protein Carbonylation by a direct Carbonyl –scavenging mechanism: focus on reactivity, selectivity, and reaction mechanisms
Reactive Carbonyl –scavenging Ability of 2-Aminoimidazoles: 2-Amino-1-methylbenzimidazole and 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
Carbonyl scavenging and chemical chaperon like function of essential amino acids attenuates non-enzymatic glycation of albumin
Potential of Birds to Serve as Pathology-Free Models of Type 2 Diabetes, Part 2: Do High Levels of Carbonyl –scavenging Amino Acids (eg., Taurine) and Low …
Carbonyl scavenging as an Antioxidant Neuroprotective Strategy for Acute Traumatic Brain Injury
Phytochemicals from berries and grapes inhibited the formation of advanced glycation end‐products by scavenging reactive Carbonyls
A carnosine analog mitigates metabolic disorders of obesity by reducing Carbonyl stress
Levels of Crotonaldehyde and 4-hydroxy-(E)-2-nonenal and Expression of Genes Encoding Carbonyl –scavenging Enzyme at Critical Node During Rice Seed …
Carbonyl –scavenging ability of phenolic compounds: A second barrier defense against the damage caused by lipid oxidation and oxidative stress
Inhibition of glyoxylate conversion to oxalate in cultured human cells by the Carbonyl –scavenging drug, aminoguanidine
Oligomeric procyanidins of lotus seedpod inhibits the formation of advanced glycation end-products by scavenging reactive Carbonyls
Melatonin is not a Carbonyl Scavenger
In vitro investigation on the antiglycative and Carbonyl trapping activities of hydroxytyrosol
Diabetes and Pancreatic Cancer—A Dangerous Liaison Relying on Carbonyl Stress
Cranberry phytochemicals inhibit glycation of human hemoglobin and serum albumin by scavenging reactive Carbonyls
Phenelzine Protects Brain Mitochondrial Function In Vitro and In Vivo following Traumatic Brain Injury by scavenging the Reactive Carbonyls 4-Hydroxynonenal and …
Antioxidant therapies for traumatic brain injury
A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging Carbonyl intermediates of carbohydrate and lipid degradation
Carnosine and the processes of ageing
In vitro and in vivo antidiabetic and antiglycation properties of apium graveolens in type 1 and 2 diabetic rats
Insoluble dietary fibre scavenges reactive Carbonyl species under simulated physiological conditions: The key role of fibre-bound polyphenols
Inhibitory effect of rosehip (Rosa canina L.) on the formation of advanced glycation endproducts by scavenging reactive Carbonyls
Glycative stress and anti-aging: 9. Glycative stress and schizophrenia.
Cyanidin-3-O-glucoside functions like chemical chaperone and attenuates the glycation mediated amyloid formation in albumin
Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose …
Pathological role of acrolein in neurotrauma and neurodegeneration
Methylglyoxal induces DNA crosslinks in ECV304 cells via a reactive oxygen species-independent protein Carbonylation pathway
High-spin Fe 3 complexes of some AGE inhibitors.
116 PYRIDOXAMINE DID NOT HAVE A MARKED HYPOLIPIDEMIC EFFECT IN LOW DENSITY LIPOPROTEIN DEFICIENT MICE: A MODEL FOR STUDYING THE …
Structure–Activity Relationship (SAR) of Phenolics for 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Formation in Phenylalanine/Creatinine Reaction …
Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive …
Reactive diCarbonyl scavenging effectively reduces MPO-mediated oxidation of HDL and restores PON1 activity
Dietary supplementation with β-alanine failed to increase ultimate pH and to improve meat quality in pigs
A significant inhibitory effect on advanced glycation end product formation by catechin as the major metabolite of lotus seedpod oligomeric procyanidins
Antimelanoma activity of apoptogenic Carbonyl Scavengers
Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low …
Carnosine and its possible roles in nutrition and health
Identification of α-diCarbonyl Scavengers for cellular protection against Carbonyl stress
Sinigrin, a major glucosinolate from cruciferous vegetables restrains non-enzymatic glycation of albumin
The triple defensive barrier of phenolic compounds against the lipid oxidation-induced damage in food products
Linolenic acid prevents early and advanced glycation end-products (AGEs) modification of albumin
Antiglycation activity of lipophilized epigallocatechin gallate (EGCG) derivatives
Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro
Potentialities and pitfalls accompanying chemico-pharmacological strategies against endogenous electrophiles and Carbonyl stress
Indole: a promising scavenging agent for methylglyoxal and related Carbonyls in tryptophan containing maillard model systems
Pyridoxamine as a multifunctional pharmaceutical: targeting pathogenic glycation and oxidative damage
MITOCHONDRIAL AND NEUROPROTECTIVE EFFECTS OF PHENELZINE RELATED TO scavenging OF NEUROTOXIC LIPID PEROXIDATION PRODUCTS
Protein Carbonylation
Identification of oxidatively modified proteins in salt-stressed Arabidopsis: a Carbonyl -targeted proteomics approach
On the relationship between energy metabolism, proteostasis, aging and Parkinson’s disease: possible causative role of methylglyoxal and alleviative …
Carbonyl Scavengers as pharmacotherapies in degenerative disease: Hydralazine repurposing and challenges in clinical translation
Cinnamon bark proanthocyanidins as reactive Carbonyl Scavengers to prevent the formation of advanced glycation endproducts
Protective effects of natural polyphenols in reactive Carbonyls pecies/lipid peroxidation-induced toxicity
Reactive diCarbonyl scavenging effectively reduces MPO-mediated oxidation of HDL and preserves HDL atheroprotective functions
Inactivation of Carbonyl -detoxifying enzymes by H2O2 is a trigger to increase Carbonyl load for initiating programmed cell death in plants
Lipid peroxidation in brain or spinal cord mitochondria after injury
Catechins in green tea powder (matcha) are heat-stable Scavengers of acrolein, a lipid peroxide-derived reactive Carbonyl species
Interaction pattern of histidine, carnosine and histamine with methylglyoxal and other Carbonyl compounds
Carnosine content in the porcine longissimus thoracis muscle and its association with meat quality attributes and carnosine-related gene expression
Naturally occurring inhibitors against the formation of advanced glycation end-products
Neuroprotectants: Reactive Oxygen Species (ROS) Based
Isoferulic acid prevents methylglyoxal-induced protein glycation and DNA damage by free radical scavenging activity
2-Alkenal-scavenging ability of m-diphenols
Investigations on the effect of broccoli and wine sulphur compounds on glyoxal scavenging under simulated physiological conditions
Reactive Carbonyl species: a missing link in ROS signaling
Neuroscience Honours Projects-2009
Carnosine as a Putative Antioxidant in Usage Against Liver Disease
Glycyrrhizic acid scavenges reactive Carbonyl species and attenuates glycation-induced multiple protein modification: an in vitro and in silico study
DNA damage by Carbonyl stress in human skin cells
The role of taurine in diabetes and the development of diabetic complications
Synthesis, characterisation and reactivity of group six alkylidynes bearing the tridentate phosphine PPh (C2H4PPh2) 2-‘triphos’. Crystal structure of mer-[W (NCMe)(≡ …
Inhibitory effects of hyperoside and quercitrin from Zanthoxylum bungeanum Maxim. leaf on 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine formation by …
Parallel synthesis of 1, 2, 3-thiadiazoles employing a” catch and release” strategy
Glycation, ageing and carnosine: are carnivorous diets beneficial?
Inhibitory effect of sugarcane molasses extract on the formation of Nε-(carboxymethyl) lysine and Nε-(carboxyethyl) lysine
Mechanisms of methimazole cytotoxicity in isolated rat hepatocytes
Carbonyl Chemistry and the Formation of Heterocyclic Aromatic Amines with the Structure of Aminoimidazoazaarene
Müller glial dysfunction during diabetic retinopathy in rats is reduced by the acrolein-scavenging drug, 2-hydrazino-4, 6-dimethylpyrimidine
Traditional reactive Carbonyl Scavengers do not prevent the Carbonylation of brain proteins induced by acute glutathione depletion
Toxicity of smoke extracts towards A549 lung cells: role of acrolein and suppression by Carbonyl Scavengers
Lipid peroxide-derived short-chain Carbonyls mediate hydrogen peroxide-induced and salt-induced programmed cell death in plants
Diabetes promotes invasive pancreatic cancer by increasing systemic and tumour Carbonyl stress in Kras G12D/+ mice
Vanillin restrains non-enzymatic glycation and aggregation of albumin by chemical chaperone like function
Newer pharmacological approaches for antioxidant neuroprotection in traumatic brain injury
Autoxidative glycosylation: free radicals and glycation theory.
Antagonism between lipid-derived reactive Carbonyls and phenolic compounds in the Strecker degradation of amino acids
Vitamin A and E Homologues Impacting the Fate of Acrylamide in Equimolar Asparagine-Glucose Model System
Regiospecific solid-phase synthesis of substituted 1, 2, 3-triazoles
Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive Carbonyl species
Lipoxidation‐derived reactive Carbonyl species as potential drug targets in preventing protein Carbonylation and related cellular dysfunction
Chaperone heat shock protein 90 mobilization and hydralazine cytoprotection against acrolein-induced Carbonyl stress
Investigting the Cytoprotective Mechanisms of VIitamins B6 and B1 against Endogenous Toxin-induced Oxidative Stress
Pyridoxamine: the many virtues of a maillard reaction inhibitor
Impact and inhibitory mechanism of phenolic compounds on the formation of toxic Maillard reaction products in food
Cytoprotective effects of hydrophilic and lipophilic extracts of Pistacia vera against oxidative versus Carbonyl stress in rat hepatocytes
In vitro attenuation of acrolein-induced toxicity by phloretin, a phenolic compound from apple
Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and Carbonyl Scavenger phenelzine
Analysis of reactive Carbonyl species generated under oxidative stress
Assessment of Carnosine Functional Properties during in vitro Digestion of Meat Differing in Composition and Cooking Conditions
An interspecies comparison of normal levels of glycosylated hemoglobin and glycosylated albumin.
Isoferulic acid prevents methylglyoxal-induced protein glycation and DNA damage by free radical scavenging activity
Protective effects of ferulic acid and related polyphenols against glyoxal-or methylglyoxal-induced cytotoxicity and oxidative stress in isolated rat hepatocytes
Pyridoxamine protects proteins from functional damage by 3-deoxyglucosone: mechanism of action of pyridoxamine
Phenolic compounds reduce formation of Nε-(carboxymethyl) lysine and pyrazines formed by Maillard reactions in a model bread system
Amodiaquine-induced toxicity in isolated rat hepatocytes and the cytoprotective effects of taurine and/or N-acetyl cysteine
Synthesis and Comparison of Antioxidant Properties of Indole‐Based Melatonin Analogue Indole Amino Acid Derivatives
Taurine Treatment for Complications of Diabetes
Design of New Probes for Oxidized Amino Acids Localization
Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes
Screening and characterization of antiglycoxidant anthocyanins from Vaccinium myrtillus fruit using DPPH and methylglyoxal pre-column HPLC assays
Birds as pathology-free models of type II diabetes
Potential of Vasoprotectives to Inhibit Non-Enzymatic Protein Glycation, and Reactive Carbonyl and Oxygen Species Uptake
Identification of single nucleotide polymorphisms in carnosine-related genes and effects of genotypes on pork meat quality attributes
2-Amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine (PhIP) formation and fate: an example of the coordinate contribution of lipid oxidation and Maillard reaction to the …
Reduced cellular glucose transport confers natural protection against dextrose‐induced superoxide generation and endoplasmic reticulum stress in domestic hen
Detoxification of aldehydes by histidine-containing dipeptides: from chemistry to clinical implications
Fluorimetric screening assay for protein Carbonyl evaluation in biological samples
Energy metabolism, altered proteins, sirtuins and ageing: converging mechanisms?
Lipid peroxide-derived reactive Carbonyl species as mediators of oxidative stress and signaling
Antioxidant therapies in traumatic brain and spinal cord injury
Cu2+ complexes of some AGEs inhibitors
Formation and Prediction of PhIP, Harman, and Norharman in Chemical Model Systems Containing Epicatechin under Various Reaction Conditions
Strategies to increase the oxidative stability of cold pressed oils
Inhibition of resveratrol glucosides (REs) on advanced glycation endproducts (AGEs) formation: Inhibitory mechanism and structure-activity relationship
Simple noninvasive measurement of skin autofluorescence
Carnosine quenches the reactive Carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation
Inhibitory mechanism of naringenin against carcinogenic acrylamide formation and nonenzymatic browning in Maillard model reactions
Glycoxidation of biological macromolecules: a critical approach to halt the menace of glycation
Carnosine and carnosine-related antioxidants: a review
Reactive Carbonyl species activate caspase-3-like protease to initiate programmed cell death in plants
New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration
Hydralazine rescues PC12 cells from acrolein‐mediated death
Understanding the role of 3-O-Acetyl-11-keto-β-boswellic acid in conditions of oxidative-stress mediated hepatic dysfunction during benzo (a) pyrene induced toxicity
Significance of proximal tubular metabolism of advanced glycation end products in kidney diseases
Controlling Amino Acid Degradations Produced by Reactive Carbonyls in Foods: A Review on the Role of Reaction Conditions for the Preferential Formation of either …
Lipid metabolites in the pathogenesis and treatment of neovascular eye disease
Development of a neuroprotective potential algorithm for medicinal plants
Iron chelation inhibits the development of pulmonary vascular remodeling
Pyridoxamine scavenges protein Carbonyls and inhibits protein aggregation in oxidative stress-induced human HepG2 hepatocytes
The ªResin-Capture±Releaseº Hybrid Technique: A Merger between Solid-and Solution-Phase Synthesis
Glucose and reactive oxygen species
Effect of cysteine on methylglyoxal-induced renal damage in mesangial cells
Novel inhibitors of advanced glycation endproducts
Toxicologically relevant aldehydes produced during the frying process are trapped by food phenolics
Protective actions of anserine under diabetic conditions
Identification of compounds that contribute to trigeminal burn in aqueous ethanol solutions
Hydralazine Modifies Aβ Fibril Formation and Prevents Modification by Lipids in Vitro
Effects of maté tea intake on ex vivo LDL peroxidation induced by three different pathways
Use of nucleophilic compounds, and their combination, for acrylamide removal
Intermolecular protein cross-linking during acrolein toxicity: efficacy of Carbonyl Scavengers as inhibitors of heat shock protein-90 cross-linking in A549 cells
The inhibition of oleanolic acid on protein non-enzymatic glycation
Hepatoprotective effect of boldine in a bile duct ligated rat model of cholestasis/cirrhosis
Amelioration of nicotinamide adenine dinucleotide phosphate–oxidase mediated stress reduces cell death after blast-induced traumatic brain injury
Characterization of modified proteins in plasma from a subtype of schizophrenia based on Carbonyl stress: Protein Carbonyl is a possible biomarker of psychiatric …
Acrolein and chloroacetaldehyde: an examination of the cell and cell-free biomarkers of toxicity
Antimalarial drugs-induced hepatic injury in rats and the protective role of carnosine
Formation of heterocyclic aromatic amines with the structure of aminoimidazoazarenes in food products
Syringic acid (SA)‒a review of its occurrence, biosynthesis, pharmacological and industrial importance
Water-soluble α, β-unsaturated aldehydes of cigarette smoke induce Carbonylation of human serum albumin
Polyphenols with antiglycation activity and mechanisms of action: A review of recent findings
Investigations on the effect of amino acids on acrylamide, pyrazines, and Michael addition products in model systems
White tea-a cost effective alternative to EGCG in fight against benzo (a) pyrene (BaP) induced lung toxicity in SD rats
Ethylene elimination upon addition of acids to the μ-ethenyl complex [Fe2 (CO) 4 (μ-η2-HC= CH2)(μ-PCy2)(μ-dppm)]: Synthesis of halide-and carboxylate-bridged …
Diets involved in PPAR and PI3K/AKT/PTEN pathway may contribute toneuroprotection in a traumatic brain injury
Antiglycation effects and reactive Carbonyl trapping capacity of berry and grape phytochemicals
Synergy Effects of Metformin and Berberine on Glyoxal-induced Carbonyl Stress in Isolated Rat Liver Mitochondria
Advanced glycation endproducts: what is their relevance to diabetic complications?
Rescuing hepatocytes from iron-catalyzed oxidative stress using vitamins B1 and B6
Commercial luncheon meat products and their in vitro gastrointestinal digests contain more protein Carbonyl compounds but less lipid oxidation products compared to …
Protective effects of dietary carnosine during in‐vitro digestion of pork differing in fat content and cooking conditions
Protective role of Clitoria ternatea L. flower extract on methylglyoxal-induced protein glycation and oxidative damage to DNA
Functionalized polymers—emerging versatile tools for solution‐phase chemistry and automated parallel synthesis
Effects of cranberry powder on biomarkers of oxidative stress and glucose control in db/db mice
Maillard reactions in hyperthermophilic archaea: Implications for better understanding of non-enzymatic glycation in biology
Ferulic acid prevents methylglyoxal-induced protein glycation, DNA damage, and apoptosis in pancreatic β-cells
Solution phase synthesis of a combinatorial library of chalcones and flavones as potent cathepsin V inhibitors
Paradoxical effect of methimazole on liver mitochondria: In vitro and in vivo
Cocoa melanoidins reduce the formation of dietary advanced glycation end-products in dairy mimicking system
New Pregnane Glycosides Isolated from Caralluma hexagona Lavranos as Inhibitors of α-Glucosidase, Pancreatic Lipase, and Advanced Glycation End Products …
Contribution of Phenolic Compounds to Food Flavors: Strecker-Type Degradation of Amines and Amino Acids Produced by o- and p-Diphenols
Interconversion and Acrolein-Trapping Capacity of Cardamonin/Alpinetin and Their Metabolites In Vitro and In Vivo
A review on prevention of glycation of proteins: Potential therapeutic substances to mitigate the severity of diabetes complications
Hepatoprotective Effect of Acetylated Amino Acid on Methimazole Induced Hepatotoxicity in Mice
Nordihydroguaiaretic acid prevents glycation induced structural alterations and aggregation of albumin
A Comprehensive Review on Source, Types, Effects, Nanotechnology, Detection, and Therapeutic Management of Reactive Carbonyl Species Associated with …
Effects of enzyme induction and/or glutathione depletion on methimazole-induced hepatotoxicity in mice and the protective role of N-acetylcysteine
Hepatocyte cytotoxicity induced by hydroperoxide (oxidative stress model) or glyoxal (Carbonylation model): prevention by bioactive nut extracts or catechins
Inhibition of glycation and aldose reductase activity using dietary flavonoids: A lens organ culture studies
Inhibitory effect of lotus seedpod oligomeric procyanidins on advanced glycation end product formation in a lactose-lysine model system
Could carnosine or related structures suppress Alzheimer’s disease?
Lipoic acid as a novel treatment for Alzheimer’s disease and related dementias
Beneficial effects of carnosine and carnosine plus vitamin E treatments on doxorubicin-induced oxidative stress and cardiac, hepatic, and renal toxicity in rats
Scavenger strategies in organic synthesis–Part One
Protective effect of carnosine and N-acetylcysteine against sodium nitrite-induced oxidative stress and DNA damage in rat intestine
Effects of Maté Tea Intake on ex Vivo LDL Peroxidation Induced by Three Different Pathways
D-penicillamine and other low molecular weight thiols: review of anticancer effects and related mechanisms
Protective effect of hydroalcoholic extract of Pistacia vera against gentamicin-induced nephrotoxicity in rats
Trapping of phenylacetaldehyde as a key mechanism responsible for naringenin’s inhibitory activity in mutagenic 2-amino-1-methyl-6-phenylimidazo [4, 5-b] pyridine …
Vitamin B6: beyond coenzyme functions
Carnosine and N‐acetyl cysteine protect against sodium nitrite‐induced oxidative stress in rat blood
Transforming dietary peptides in promising lead compounds: the case of bioavailable carnosine analogs
113 ANABOLIC AND ANDROGENIC ACTIVITY OF “DESIGNER STEROID”, TETRAHYDROGESTRINONE
114 LINKAGES BETWEEN THE ULTRADIAN PATTERNS OF GROWTH HORMONE AND GHRELIN: EXTERNAL VERSUS INTERNAL CUEING
115 EXOGENOUS TESTOSTERONE ALONE OR WITH FINASTERIDE INCREASES PHYSICAL PERFORMANCE, GRIP STRENGTH, AND LEAN BODY MASS IN …
112 PARATHORMONE ESTIMATION IN FINE NEEDLE ASPIRATE-A NOVEL TECHNIQUE FOR PRE-OPERATIVE LOCALIZATION OF PARATHYROID ADENOMAS
Food processing antioxidants
Pharmacological antioxidant strategies as therapeutic interventions for COPD
Phenolics as Carbonyl Scavengers : an additional protection against lipid oxidative damage in foods.
Green tea extract suppresses the age-related increase in collagen crosslinking and fluorescent products in C57BL/6 mice
Antioxidant pharmacological therapies for COPD
Rutin inhibits the in vitro formation of advanced glycation products and protein oxidation more efficiently than quercetin
Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive …
Glycation as an atherogenic modification of LDL
The Contributing Role of Lipid Peroxidation and Protein Oxidation in the Course of CNS Injury Neurodegeneration and Neuroprotection
Protective effect of edaravone on rat testis after valproic acid treatment
Glyoxal and methylglyoxal: autoxidation from dihydroxyacetone and polyphenol cytoprotective antioxidant mechanisms
New functions of glucosamine as a Scavenger of the lipid peroxidation product malondialdehyde
Natural antioxidant polyphenols on inflammation management: Anti-glycation activity vs metalloproteinases inhibition
Decrypting the potential role of α-lipoic acid in Alzheimer’s disease
Anti-ageing potential of carnosine: approaches toward successful ageing
4‐hydroxynonenal (HNE), a toxic aldehyde in French fries from fast food restaurants
Cigarette smoke component acrolein modulates chromatin assembly by inhibiting histone acetylation
Exploring the space of histidine containing dipeptides in search of novel efficient RCS sequestering agents
An emerging molecular target in melanoma: cellular Carbonyl stress and the inhibition of mitochondrial survival pathways by Carbonyl Scavenger agents
Biosynthesized ZnO-NPs from Morus indica attenuates methylglyoxal-induced protein glycation and RBC damage: In-vitro, in-vivo and molecular docking study
The role of lipoxidation in the pathogenesis of diabetic retinopathy
Oxidative damage mechanisms in traumatic brain injury and antioxidant neuroprotective approaches
Amelioration of cardiotoxic impacts of diclofenac sodium by vitamin B complex
Ruthenium Complexes of CP3: A New Carbon-Centered Polydentate Podand Ligand
Archive of S Archive
A hypothesis: moderate consumption of alcohol contributes to lower prevalence of type 2 diabetes due to the scavenging of alpha-diCarbonyls by dietary polyphenols
Renal microvascular injury in diabetes: RAGE and redox signaling
A concise appraisal of lipid oxidation and lipoxidation in higher plants
Oxidative damage in human gingival fibroblasts exposed to cigarette smoke
The butter flavorant, diacetyl, forms a covalent adduct with 2-deoxyguanosine, uncoils DNA, and leads to cell death
Long-term treatment with shengmai san-derived herbal supplement (Wei Kang Su) enhances antioxidant response in various tissues of rats with protection against …
L-cysteine is a potent inhibitor of protein glycation on both albumin and LDL, and prevents the diabetic complications in diabetic–atherosclerotic rat
Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin …
Antiglycation study of HMG-R inhibitors and tocotrienol against glycated BSA and LDL: A comparative study
Mass spectrometry-based metabolomics and chemometric analysis of Pu-erh teas of various origins
2-Deoxy-D-ribose induces cellular damage by increasing oxidative stress and protein glycation in a pancreatic β-cell line
Overproduction of a rice aldo–keto reductase increases oxidative and heat stress tolerance by malondialdehyde and methylglyoxal detoxification
ASSAY DEVELOPMENT FOR THE PHARMACOKINETIC STUDY OF A NOVEL NON-MELANOMA SKIN CANCER DRUG
Advanced glycation inhibition and protection against endothelial dysfunction induced by coumarins and procyanidins from Mammea neurophylla
scavenging diCarbonyls with 5′-O-pentyl-pyridoxamine improves insulin sensitivity and reduces atherosclerosis through modulating inflammatory Ly6Chi monocytosis …
Metformin scavenges formaldehyde and attenuates formaldehyde‐induced bovine serum albumin crosslinking and cellular DNA damage
Emerging cardioprotective mechanisms of vitamin B6: a narrative review
Merging Solid‐Phase and Solution‐Phase Synthesis: The “Resin‐Capture‐Release” Hybrid Technique
Synthesis and evaluation of polyunsaturated fatty acid-phenol conjugates as anti-Carbonyl -stress lipophenols
Synthesis, characterization and detection of novel protein modifications in vitro and in vivo:[kumulative Dissertation]
Therapeutic potential of common culinary herbs and spices of Mauritius
The periodontal pathogen Porphyromonas gingivalis cleaves apoB‐100 and increases the expression of apoM in LDL in whole blood leading to cell proliferation
Biomarkers of exposure to endogenous oxidative and aldehyde stress
Methylglyoxal down-regulates the expression of cell cycle associated genes and activates the p53 pathway in human umbilical vein endothelial cells
EFFECT OF ADDING POLYPHENOLIC FRACTIONS ON THE ACROLEIN AND TRANS FATTY ACID CONTENTS DURING DEEP FRYING AND HEATING OF …
Atmospheric concentrations of Semivolatile bifunctional Carbonyl compounds and the contribution from motor vehicles
Lipid peroxidation-derived reactive aldehydes directly and differentially impair spinal cord and brain mitochondrial function
Glutathione in cerebral microvascular endothelial biology and pathobiology: implications for brain homeostasis
Investigation of serum amino acids involved in gallic acid detoxification of formaldehyde by liquid chromatography/tandem mass spectrometry and neutral loss scan
Diet and Obesity-Induced Methylglyoxal Production and Links to Metabolic Disease
Natural Products as a Source of Inspiration for Novel Inhibitors of Advanced Glycation Endproducts (AGEs) Formation
On the origin of free and bound staling aldehydes in beer
Cytoprotective effects of silafibrate, a newly-synthesised siliconated derivative of clofibrate, against acetaminophen‑induced toxicity in isolated rat hepatocytes
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions
Troxerutin imparts preservative effects on albumin by preventing Maillard reaction-mediated early and advanced glycation modification
The glyoxalase system-a link between carbonilic stress and human therapy
Improved flavor stability by aging beer in the presence of yeast
Emerging role of thiamine therapy for prevention and treatment of early‐stage diabetic nephropathy
The cardioprotective effect of b vitamins against the toxic impact of zinc oxide-bulk compared with zinc oxide-nanoparticles induced cardiac infarction in rats
Evaluation of neurobiological and antioxidant effects of novel melatonin analogs in mice
Chronic acrolein exposure in Wistar rats: The effects of guarana extracts
Prior exposure to acrolein accelerates pulmonary inflammation in influenza A-infected mice
Evaluation of ADMA, Carbonyl groups, CAT and NKA in depressed patients with and without posttraumatic stress disorder
Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
An Evolutionary Remedy for an Abominable Physiological Mystery: Benign Hyperglycemia in Birds
Wedelolactone Mitigates Parkinsonism Via Alleviating Oxidative Stress and Mitochondrial Dysfunction Through NRF2/SKN-1
Investigation Of The Reactivities Of Monomeric And Polymeric Components In Some Foods In Digestion Conditions In Vitro
Pyridoxamine improves functional, structural, and biochemical alterations of peritoneal membranes in uremic peritoneal dialysis rats
Oxidative status of DBA/1J mice with type II collagen‐induced arthritis
Melatonin does not have any effect on proteasome activity in human dermal fibroblast.
Lipid peroxidation by-products and the metabolic syndrome
Bioactive Compounds from Morus indica as Inhibitors of Advanced Glycation End Products
Aldo–keto reductases mediate constitutive and inducible protection against aldehyde toxicity in human neuroblastoma SH-SY5Y cells
Amelioration of nicotinamide adenine dinucleotide phosphate–mediated stress reduces cell death after blast-induced traumatic brain injury
Mechanisms for oxidative stress in diabetic cardiovascular disease
Role of α-Lipoid Acid and Acetyl-L-Carnitine in Dementia
The roles of protein glycation, glycoxidation, and advanced glycation end-product formation in diabetes-induced atherosclerosis
Temporal characterization of mitochondrial bioenergetics after spinal cord injury
Advanced Glycation End Products of DNA: Quantification of N2-(1-Carboxyethyl)-2′-deoxyguanosine in Biological Samples by Liquid Chromatography …
Pharmacological and dietary antioxidant therapies for chronic obstructive pulmonary disease
Neuroprotective Strategies Following Experimental Traumatic Brain Injury: Lipid Peroxidation-derived Aldehyde scavenging and Inhibition of Mitochondrial …
A role for nanoparticles in treating traumatic brain injury
Acrolein contributes to the neuropathic pain and neuron damage after ischemic–reperfusion spinal cord injury
Key factors regulating protein Carbonylation by α, β unsaturated Carbonyls : a structural study based on a retrospective meta-analysis
Neuroactive compounds in foods: Occurrence, mechanism and potential health effects
Scavenger
Ameliorative effect of carnosine and N‐acetylcysteine against sodium nitrite induced nephrotoxicity in rats
Reactive aldehydes–second messengers of free radicals in diabetes mellitus
Effect of fat-soluble anti-oxidants in vegetable oils on acrylamide concentrations during deep-fat frying of French fries
Diiron acetylide complexes: Molecular structures of [Fe2 (CO) 4 (μ-C≡ CPh)(μ-PPh2)(μ-dppm)] and [Fe2 (CO) 3 (Ph2PC≡ CPh)(μ-C≡ CPh)(μ-PPh2)(μ-dppm)]
Traumatic brain injury alters synaptic homeostasis: implications for impaired mitochondrial and transport function
Protective effect of vitamin B complex against renotoxic tissue damage induced by diclofenac sodium in rats
Cinnamon, a promising prospect towards Alzheimer’s disease
Characterisation of intracellular molecular mechanisms modulated by carnosine in porcine myoblasts under basal and oxidative stress conditions
Wheat and rice bran as natural additives for the protection of fish oil from oxidation
Role of α-DiCarbonyl Compounds in the Inhibition Effect of Reducing Sugars on the Formation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
Iridoids are natural glycation inhibitors
Protein Carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion
Mechanism of non-enzymatic antiglycation action by coumarin: a biophysical study
Potential reactions of thermal process contaminants during digestion
Toward better dialysis compatibility: advances in the biochemistry and pathophysiology of the peritoneal membranes
Differential effects of insulin on peripheral diabetes-related changes in mitochondrial bioenergetics: involvement of advanced glycosylated end products
Molecular responses of legumes to abiotic stress: post-translational modifications of proteins and redox signaling
Tenilsetam prevents early diabetic retinopathy without correcting pericyte loss
Molecular responses of legumes to abiotic stress: post-translational modifications of proteins and redox signaling
Taurine reduces nitrosative stress and nitric oxide synthase expression in high glucose-exposed human Schwann cells
Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine
Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone
4-Hydroxy-2-nonenal, a lipid peroxidation product, as a biomarker in diabetes and its complications: challenges and opportunities
Strategies to decrease ongoing oxidant burden in chronic obstructive pulmonary disease
Inhibition of advanced glycation end products formation and inflammation in C. elegans: Studies of potential of Lyngbya sp. against expression of stress related genes …
Reduction of High Glucose-Induced Nitric Oxide Synthase Expression in Human Vascular Endothelial Cells by Ascorbic Acid and α-Tocopherol
Spatial distributions of airborne di-Carbonyls in urban and rural areas in China
Hepatocyte Cytotoxicity Induced by Hydroperoxide (Oxidative Stress Model) or DiCarbonyls (Carbonylation Model): Prevention by Bioactive Nut Extracts or …
Pharmacological applications of antioxidants: lights and shadows
Reactivity-based drug discovery using vitamin B6-derived pharmacophores
An untargeted and pseudotargeted metabolomic combination approach to identify differential markers to distinguish live from dead pork meat by liquid …
Quantitative structure–activity relationship for 4-hydroxy-2-alkenal induced cytotoxicity in L6 muscle cells
Body fat reduction without cardiovascular changes in mice after oral treatment with the MAO inhibitor phenelzine
Synthesis of cobalt-tungsten clusters with tetrahedral metallic cores using the mixed-metal complex CoW (CO) 7 (. eta. 5-C5H4Me)(CoW) as a cluster building block. X …
Metformin alleviates cholestasis-associated nephropathy through regulating oxidative stress and mitochondrial function
Exploring the Role of Elevated Lipid Peroxidation and Glutathione Peroxidase 4 in Metabolic Syndrome and Cardiac Remodeling in Obesity
An overview of pharmacological approaches for management and repair of spinal cord injuries
Glycation, Carbonyl stress, EAGLEs, and the vascular complications of diabetes
Resveratrol derivatives: a patent review (2009–2012)
Sperm motility is lost in vitro as a consequence of mitochondrial free radical production and the generation of electrophilic aldehydes but can be significantly rescued …
Properties and reactivity of the folic acid and folate photoproduct 6-formylpterin
A concise appraisal of lipid oxidation and lipoxidation in higher plants
Covalent binding antibodies suppress advanced glycation: on the innate tier of adaptive immunity
Covalent binding antibodies suppress advanced glycation: on the innate tier of adaptive
Novel metabolic disturbances in marginal vitamin B6-deficient rat heart
Small molecules and Alzheimer’s disease: misfolding, metabolism and imaging
Use of the cationic fragments [Ru (η5-C5H5)(MeCN) 3]+ and [M (η6-C6H5R)(MeCN) 3]+(M= Os, Ru; R= H, Me) as ionic coupling reagents with the anions [H2Os4 (CO …
Bifunctional Chloroplastic DJ-1B from Arabidopsis thaliana is an Oxidation-Robust Holdase and a Glyoxalase Sensitive to H2O2
Therapeutic window analysis of the neuroprotective effects of cyclosporine A after traumatic brain injury
Running title: Cytotoxicity of 4-hydroxy-2-alkenal derivatives Word count: 4183 3 Tables, 5 Figures
Commentary on some recent theses relevant to combating aging: October 2015
Bis-allylic deuterated DHA alleviates oxidative stress in retinal epithelial cells
Study on the Pharmacological Mechanism of Phthalazinone Derivatives as Potential Drugs for Alzheimer’s Disease Treatment by Network Pharmacology …
Investigation of serotonin, free and protein-bound tryptophan in Turkish hazelnut varieties and effect of roasting on serotonin content
Metformin associated with photodynamic therapy–a novel oncological direction
Role of inflammation and oxidative stress in the pathology of ageing in COPD: potential therapeutic interventions
Coordination and activation of diazoalkanes in the presence of Rh/Ru and Rh/Os metal combinations
Potential of Birds to Serve as a Pathology-Free Model of Type 2 Diabetes, Part 1: Is the Apparent Absence of the RAGE Gene a Factor in the Resistance of Avian …
Natural products as potential inhibitors of Advanced Glycation Endproducts (AGEs) and modulators of autophagy
Design and synthesis of novel bioactive peptides and peptidomimetics
Potential prophylactic impact of B vitamins against zinc oxide bulk and its nanoparticles induced kidney damage
Temporal and spatial dynamics of peroxynitrite-induced oxidative damage after spinal cord contusion injury
Environmental-stress-induced chromatin regulation and its heritability
Dietary Polyphenols and Their Gut Microbiota Metabolites as Potential Treatments for Alzheimer’s Disease
Therapeutic potential of targeting lipid aldehydes and lipoxidation end-products in the treatment of ocular disease
Molecular responses of legumes to abiotic stress: post-translational modifications of proteins and redox signaling
Comparative Proteomics at the Critical Node of Vigor Loss in Wheat Seeds Differing in Storability
A Role for Nanoparticles in Treating Traumatic Brain Injury.
Basic and clinical research against advanced glycation end products (AGEs): new compounds to tackle cardiovascular disease and diabetic complications
POSSIBLE PROTECTIVE EFFECT OF CARNOSINE ON CADMIUM-INDUCED RENAL DYSFUNCTION IN OLD RATS
Direct Hydrolysis of Hydrated Organotin Cations: Synthesis and Structural Characterization of {[n-Bu2Sn (OH2)(Phen)(O3SC6H3-2, 5-Me2)]+[2, 5-Me2C6H3SO3]-} …
Activating Protecting Groups for the Solid Phase Synthesis and Modification of Peptides, Oligonucleotides and Oligosaccharides
The Health Consequences of Fructose, its Metabolite, Dihydroxyacetone and the Hepatoprotective Effects of Selected Natural Polyphenols in Rat Hhepatocytes
Protein Carbonylation and glycation in legume nodules
An Integrated proteomic and analytical approach for elucidating the mechanism of action of histidine dipeptides and synthetic derivatives
Taurine depletion and Schwann cell dysfunction in diabetic neuropathy
Beetroot (Beta vulgaris) and lingonberry (Vaccinium vitis-idaea l.) leaves preparations antioxidative characteristics and impact on the formation of toxic maillard …
Protective effects of Clostridium butyricum against oxidative stress induced by food processing and lipid-derived aldehydes in Caco-2 cells
NOX1 supports the metabolic remodeling of HepG2 cells
Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye
Effect of Phyllanthus emblica L. fruit on improving regulation of methylglyoxal-induced insulin resistance in 3T3-L1 cells
Impact of hyperlipidemia on plasma protein binding and hepatic drug transporter and metabolic enzyme regulation in a rat model of gestational diabetes
Taurine kinetics assessed using [1,2-13C2]taurine in healthy adult humans
Amino acid effects on heterocyclic amine formation in the Maillard reaction model systems and pan-fried beef patties
A 10-Å spectroscopic ruler applied to short polyprolines
Investigating the cytotoxic mechanisms of hepatotoxicity induced by xenobiotics and their metabolites
Dietary Intervention With a Targeted Micronutrient Formulation Reduces the Visual Discomfort Associated With Vitreous Degeneration
Investigation into the reactivity and electrochemical properties of higher nuclearity clusters with nitrogen heterocyclic ligands: a chemical, electrochemical and …
The Influence of OAT1 Density and Functionality on Indoxyl Sulfate Transport in the Human Proximal Tubule: An Integrated Computational and In Vitro Study
Cyclopeptide alkaloids: isolation, structure elucidation, antiplasmodial activity and AGEs inhibiting properties
Intracellular delivery of reactive oxygen species generating polypeptide-drug conjugates for cancer therapy
Metabolism of Foodborne Heterocyclic Aromatic Amines by Lactobacillus reuteri DSM 20016
Extra-Virgin Olive Oil and Type 2 Diabetes Mellitus
Traceless solid-phase organic synthesis
Neuroprotection and functional restoration in an animal model of multiple sclerosis
Substrate Transformations Promoted by Adjacent Group 8 and 9 Metals
Oxidative Stress Reduction (Prong-3)
Cyclization of reactive Carbonyls in foods upon processing: an origin for the formation of pyridine-derived flavours and heterocyclic aromatic amines
CARNOSINE: A POTENT MODULATOR FOR DIFFERENT DISEASES
Design and synthesis of novel non peptidomimtic beta-secretase inhibitors in the treatment of Alzheimer’s disease
End-monomer dynamics in semiflexible polymers
Novel Targets for Mitochondrial Dysfunction Following Traumatic Brain Injury
Inhibition of NLRP3 ATPase activity: a new strategy to fight chronic inflammatory diseases
In silico study of NLRP3: towards selective inhibition with small molecules
Proceedings of the Merck Young Chemists’ Symposium XIX edition
Preliminary ADME/PK studies of new hDHODH inhibitors effective for treatment of acute myeloid leukaemia (AML)
Improvement of in vivo pharmacokinetic profile of M433, a potent and innovative hDHODH inhibitor.
Synthesis of [18F] Brequinar as PET Imaging probes for human dihydroorotate dehydrogenase
Synthesis, physiochemical proprieties and application of hydroxyazole systems as carboxylic acid isoster
The complexity of the blood-brain barrier and the concept of age-related brain targeting: challenges and potential of novel solid lipid-based formulations
Chemical Probe Design & Development for Assessing Protein Modification and Cross-Linking
The reactivity of stable metallacyclobutenes and vinylcarbenes
SWATH-MS based label-free quantitative analysis to investigate the proteomic effects of lactic acid bacteria on keratinocytes
Carbonyl Scavenger and antiatherogenic effects of hydrazine derivatives
The Carbonyl Scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats
Antiatherogenic effect of bisvanillyl-hydralazone, a new hydralazine derivative with antioxidant, Carbonyl Scavenger , and antiapoptotic properties
A novel polymer-based Carbonyl Scavenger for the detection of ischemic tissues
Sutures impregnated with an aldehyde-Carbonyl Scavenger reduce peritoneal adhesions
Synthesis and antioxidant activity evaluation of a syringic hydrazones family
Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors
Pomegranate phenolics inhibit formation of advanced glycation endproducts by scavenging reactive Carbonyl species
Reactive oxygen species and reactive Carbonyl species constitute a feed‐forward loop in auxin signaling for lateral root formation
Anti-melanoma activity of D-penicillamine and other Carbonyl Scavengers .
Therapeutic induction of melanoma cell apoptosis: Focus on covalent modulation of the mitochondrial permeability transition pore by Carbonyl Scavengers
The Carbonyl Scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal
Glyoxalase I disruption and external Carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons
The antihypertensive hydralazine is an efficient Scavenger of acrolein
Polysulfides protect SH-SY5Y cells from methylglyoxal-induced toxicity by suppressing protein Carbonylation : A possible physiological Scavenger for Carbonyl stress in …
Pomegranate (Punica granatum) fruit polyphenols, punicalagin, ellagic acid and gallic acid, inhibit formation of advanced glycation endproducts by scavenging …
Carnosine and related peptides: therapeutic potential in age-related disorders
Lipid oxidation products and oxidized low-density lipoproteins impair platelet-derived growth factor receptor activity in smooth muscle cells: implication in …
Rescuing neurons from necrotic death
Behaviour of protein Carbonyl groups in juvenile myocardial infarction
Design, synthesis and activity evaluation of antioxidant peptides
Outcome and prevention strategies in peritoneal adhesion formation
Selective responses of myenteric neurons to oxidative stress and diabetic stimuli
Methylglyoxal induces oxidative stress and mitochondrial dysfunction in osteoblastic MC3T3-E1 cells
Propagation of protein glycation damage involves modification of tryptophan residues via reactive oxygen species: inhibition by pyridoxamine
Development of novel antiatherogenic biaryls: design, synthesis, and reactivity
Protein Carbonylation , protein aggregation and neuronal cell death in a murine model of multiple sclerosis
Beta glucogallin, a plant-derived antioxidant and anti-inflammatory agent, alleviates corneal injury from chloropicrin exposure.
Pathological effects of glyoxalase I inhibition in SH‐SY5Y neuroblastoma cells
Photolabile linkers: exploiting labile bond chemistry to control mode and rate of hydrogel degradation and protein release
Study of Carnosine’s effect on nude mice skin to prevent UV-A damage
Actin Cys374 as a nucleophilic target of α, β-unsaturated aldehydes
LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells
Protein Carbonylation , protein aggregation and cell death in a murine model of multiple sclerosis
Exploring medical applications of a bioactive polymer
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity
Intermediate filament Carbonylation during acute acrolein toxicity in A549 lung cells: functional consequences, chaperone redistribution, and protection by bisulfite
Reactive Carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes
Albumin Protects Lung Cells against Acrolein Cytotoxicity and Acrolein-Adducted Albumin Increases Heme Oxygenase 1 Transcripts
Protein oxidation in a group of subjects with metabolic syndrome
Behaviour of Carbonyl groups in several clinical conditions: analysis of our survey
Apolipoprotein AI glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages
Acute carnosine administration increases respiratory chain complexes and citric acid cycle enzyme activities in cerebral cortex of young rats
Kidney injury-mediated disruption of intestinal lymphatics involves diCarbonyl -modified lipoproteins.
Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells
Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone derivatives
Antioxidant drugs intercalated into layered double hydroxide: Structure and in vitro release
Oxidative stress-inducing Carbonyl compounds from common foods: novel mediators of cellular dysfunction
4-Hydroxynonenal impairs transforming growth factor-β1-induced elastin synthesis via epidermal growth factor receptor activation in human and murine fibroblasts
A transient increase in lipid peroxidation primes preadipocytes for delayed mitochondrial inner membrane permeabilization and ATP depletion during prolonged …
Carnosine treatment in combination with ACE inhibition in diabetic rats
Vitamins B6, Folic Acid, and B12: Molecular functions and prevalence of deficiency in India
An interfacial oxime reaction to immobilize ligands and cells in patterns and gradients to photoactive surfaces
Elastin modification by 4-hydroxynonenal in hairless mice exposed to UV-A. Role in photoaging and actinic elastosis
Synthesis, Molecular Structure and Anti-Onchocercal Studies of 1-(Phthalazin-1 (2H)-one)[(Pyridin-2-yl) ethylidene] hydrazone
Reactive Carbonyls and Polyunsaturated Fatty Acids Produce a Hydroxyl Radical-like Species: A POTENTIAL PATHWAY…
Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive Carbonyl species?
Vitamin B6 Acquisition and Metabolism in Schistosoma mansoni
Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.
4-Hydroxynonenal contributes to angiogenesis through a redox-dependent sphingolipid pathway: prevention by hydralazine derivatives
Biogenic aldehydes as therapeutic targets for cardiovascular disease
Could carnosine suppress zinc-mediated proteasome inhibition and neurodegeneration? Therapeutic potential of a non-toxic but non-patentable dipeptide
8: 2 fluorotelomer alcohol inhibited proliferation and disturbed the expression of pro-inflammatory cytokines and antigen-presenting genes in murine macrophages
Group members
Mutations in PROSC disrupt cellular pyridoxal phosphate homeostasis and cause vitamin-B6-dependent epilepsy
Reduced muscle carnosine content in type 2, but not in type 1 diabetic patients
Inhibitory activity of pigments in tomato on AGEs of food simulation system in accelerated storage condition
N-Terminal 2, 3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal Scavengers to inhibit advanced glycation endproduct (AGE) formation
Antiatherogenic and antitumoral properties of Opuntia cladodes: inhibition of low density lipoprotein oxidation by vascular cells, and protection against the cytotoxicity …
Hyperlipidemia and renal disease: the use of animal models in understanding pathophysiology and approaches to treatment.
Proatherogenic effects of 4-hydroxynonenal
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells—protection by Carbonyl Scavengers
Advanced glycation endproducts cause lipid peroxidation in the human neuronal cell line SH-SY5Y
Role of oxidative stress in the genesis of atherosclerosis and diabetes mellitus: a personal look back on 50 years of research
Hemoglobin induces oxidative stress and mitochondrial dysfunction in oligodendrocyte progenitor cells
Protein modification by acrolein: relevance to pathological conditions and inhibition by aldehyde sequestering agents
Isoniazid as an Aldehdye Scavenger : Analysis of Its Kinetics, Selectivity, and Practicality in Purifying Organic Reactions
Accumulation of Carbonyl proteins in the brain of mouse model for methylglyoxal detoxification deficits
Reaction of metformin with diCarbonyl compounds. Possible implication in the inhibition of advanced glycation end product formation
Vitamin B6 Acquisition and
Gemigliptin, a novel dipeptidyl peptidase-4 inhibitor, exhibits potent anti-glycation properties in vitro and in vivo
5 Lipoic Acid as an
Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts
Protein adduct-trapping by hydrazinophthalazine drugs: mechanisms of cytoprotection against acrolein-mediated toxicity
A Bridging Carbonyl of Unlikely Geometry: On the True Nature of the Technetium Complex [Tc2 (μ-CO) 2 (CO) 6 (NC5H5) 2]
Protein disulfide isomerase modification and inhibition contribute to ER stress and apoptosis induced by oxidized low density lipoproteins
Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E
Inhibitory effect of apocynin on methylglyoxal‐mediated glycation in osteoblastic MC3T3‐E1 cells
Effect of metformin administration on plasma advanced glycation end product levels in women with polycystic ovary syndrome
An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis
Oxidant signaling for interleukin-13 gene expression in lung smooth muscle cells
Protective mechanisms of Cucumis sativus in diabetes-related modelsof oxidative stress and Carbonyl stress
Cite as: Bockeria LA, Movsesyan RR, Popov AE, Bledzhyants GA, Egorov DN, Pashchenko OI, Danilov DV, Egorova IF. The history of the intraoperative …
High resolution magic angle spinning NMR spectroscopy reveals that pectoralis muscle dystrophy in chicken is associated with reduced muscle content of anserine …
Oxidation of LDL, atherogenesis, and apoptosis
Peptide− small molecule hybrids via orthogonal deprotection− chemoselective conjugation to cysteine-anchored scaffolds. A model study
Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone derivatives
Stability studies of the effect of crosslinking on hydrochlorothiazide release.
Possible benefit of dietary carnosine towards depressive disorders
Synthesis, Molecular Structure, Anti-Plasmodial, Antimicrobial and Anti-Oxidant Screening of (E)-1-(Phthalazin-1-yl)-1-[(Pyridin-2-yl) Ethylidene] Hydralazine …
Anti-cancer actions of carnosine and the restoration of normal cellular homeostasis
Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone…
and Alzheimer’s Disease
Evaluation of Asteraceae herbal extracts in the management of diabetes and obesity. Contribution of caffeoylquinic acids on the inhibition of digestive enzymes activity …
Glycolaldehyde induces growth inhibition and oxidative stress in human breast cancer cells
Olive leaf extracts protect cardiomyocytes against 4-hydroxynonenal-induced toxicity in vitro: comparison with oleuropein, hydroxytyrosol, and quercetin
Levels of higher alcohols inducing aroma changes and modulating experts’ preferences in wine model solutions
The AGE inhibitor pyridoxamine inhibits development of retinopathy in experimental diabetes
Post-Amadori Reactions of Serum Proteins
Carbonyl stress in diabetics with acute coronary syndrome
Diabetes depresses synaptic transmission in sympathetic ganglia by inactivating nAChRs through a conserved intracellular cysteine residue
Effects of carnosine on prooxidant–antioxidant status in heart tissue, plasma and erythrocytes of rats with isoproterenol-induced myocardial infarction
Impairment of electron transfer chain induced by acute carnosine administration in skeletal muscle of young rats
LR-90 a new advanced glycation endproduct inhibitor prevents progression of diabetic nephropathy in streptozotocin-diabetic rats
Phenelzine reduces the oxidative damage induced by peroxynitrite in plasma lipids and proteins
Synthesis and evaluation of antioxidant phenolic diaryl hydrazones as potent antiangiogenic agents in atherosclerosis
Histone Carbonylation in vivo and in vitro
Biological functions of histidine-dipeptides and metabolic syndrome
Protein Carbonylation in human diseases
Inhibition of advanced glycation end-product formation on eye lens protein by rutin
Phenelzine mitochondrial functional preservation and neuroprotection after traumatic brain injury related to scavenging of the lipid peroxidation-derived aldehyde 4 …
Therapeutic options to reduce advanced glycation end products in patients with diabetes mellitus: A review
Surface Modification with Orthogonal Photosensitive Silanes for Sequential Chemical Lithography and Site‐Selective Particle Deposition
The protective effects of sciadopitysin against methylglyoxal‐induced cytotoxicity in cultured pancreatic β‐cells
Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity
Effect of carnosine on renal function, oxidation and glycation products in the kidneys of high-fat diet/streptozotocin-induced diabetic rats
Perspectives on molecular biomarkers of oxidative stress and antioxidant strategies in traumatic brain injury
Alternative antiglycation mechanisms: are spermine and fructosamine-3-kinase part of a Carbonyl damage control pathway?
Oxidative Stress and Balance in Neurodegenerative Diseases
Natural antioxidants as food and feed additives to promote health benefits and quality of meat products: A review
Melanoidins from coffee, cocoa, and bread are able to scavenge α-diCarbonyl compounds under simulated physiological conditions
Carbazate functionalized cellulose beads as potential Scavengers specific for Carbonylated proteins
Bergenin increases osteogenic differentiation and prevents methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblasts
3-Bromopyruvate induces rapid human prostate cancer cell death by affecting cell energy metabolism, GSH pool and the glyoxalase system
Advanced glycation end product precursors impair ABCA1-dependent cholesterol removal from cells
Carnosine catalyzes the formation of the oligo/polymeric products of methylglyoxal
Amplification of AngII-dependent cell contraction by glyoxal: Implication of cell mechanical properties and actomyosin activity
Bone morphogenic protein-4-induced oxidant signaling via protein Carbonylation for endothelial dysfunction
Acrolein toxicity at advanced age: present and future
AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?
Research frontiers in the chemistry of Criegee intermediates and tropospheric ozonolysis
Carbazate modified dextrans as Scavengers for Carbonylated proteins
Protective effect of liquiritigenin against methylglyoxal cytotoxicity in osteoblastic MC3T3-E1 cells
Polymorphisms in NAT2 gene and atherosclerosis in an Algerian population
Anserine and carnosine supplementation in the elderly: Effects on cognitive functioning and physical capacity
Targeting reactive Carbonyl species with natural sequestering agents
Hydralazine protects nigrostriatal dopaminergic neurons from MPP+ and MPTP induced neurotoxicity: Roles of Nrf2-ARE signaling pathway
Carnosine and its (S)-Trolox™ derivative protect animals against oxidative stress
4-Hydroxynonenal Contributes to Fibroblast Senescence in Skin Photoaging Evoked by UV-A Radiation
Carnosine in health and disease
Isotopic labelling for the characterisation of HNE-sequestering agents in plant-based extracts and its application for the identification of anthocyanidins in black rice …
Dietary carnosine prevents early atherosclerotic lesion formation in apolipoprotein E–Null mice
Advanced glycation end products mediated cellular and molecular events in the pathology of diabetic nephropathy
Isolevuglandins (isoLGs) as toxic lipid peroxidation byproducts and their pathogenetic role in human diseases
Signaling properties of 4-hydroxyalkenals formed by lipid peroxidation in diabetes
Oral phenelzine treatment mitigates metabolic disturbances in mice fed a high-fat diet
Acrolein Scavenger Hydralazine Prevents Streptozotocin‐Induced Painful Diabetic Neuropathy and Spinal Neuroinflammation in Rats
The role of advanced glycation end products in various types of neurodegenerative disease: a therapeutic approach
The mechanism of the thermal isomerization of 1, 2-diolates. Is the pinacol coupling reaction reversible?
Cell death and diseases related to oxidative stress: 4-hydroxynonenal (HNE) in the balance
Deoxyactein protects pancreatic β-cells against methylglyoxal-induced oxidative cell damage by the upregulation of mitochondrial biogenesis
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E−/− mice
Amine-functionalized nanoporous thin films from a poly (ethylene oxide)-block-polystyrene diblock copolymer bearing a photocleavable o-nitrobenzyl carbamate …
Limonene protects osteoblasts against methylglyoxal-derived adduct formation by regulating glyoxalase, oxidative stress, and mitochondrial function
Carnosine effect on advanced lipoxidation end-products: A brief review on tissues
Computational approaches in the rational design of improved Carbonyl quenchers: focus on histidine containing dipeptides
Transforming growth factor-β1/Smad3 signaling and redox status in experimentally induced nephrotoxicity: impact of carnosine
A carnosine intervention study in overweight human volunteers: bioavailability and reactive Carbonyl species sequestering effect
Sweet and sour-oxidative and Carbonyl stress in neurological disorders
Photolabile protecting groups and linkers
N,N′-Bis(diphenylphosphino)diaminophenylphosphine Ligands for Chromium-Catalyzed Selective Ethylene Oligomerization Reactions
The effects of α-lipoic acid against testicular ischemia-reperfusion injury in rats
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer’s disease
Low-sodium diet induces atherogenesis regardless of lowering blood pressure in hypertensive hyperlipidemic mice
The role of oxidative stress in renal injury related to obesity
Methylglyoxal, oxidative stress, and hypertension
Carnosine supplementation improves serum resistin concentrations in overweight or obese otherwise healthy adults: a pilot randomized trial
The hydrolyzable gallotannin, penta-O-galloyl-β-D-glucopyranoside, inhibits the formation of advanced glycation endproducts by protecting protein structure
Molecular mechanisms of acrolein toxicity: relevance to human disease
Hydralazine derivative of aldehyde: A new type of [M − H]+ ion formed in electrospray ionization mass spectrometry
Pathophysiology of diabetic erectile dysfunction: potential contribution of vasa nervorum and advanced glycation endproducts
The extract of aster koraiensis prevents retinal pericyte apoptosis in diabetic rats and its active compound, chlorogenic acid inhibits AGE formation and AGE/RAGE …
Protective Effect of Carnosine Against Zn-Mediated Toxicity in Cortical Neuronal Cells
Low plasma carnosinase activity promotes carnosinemia after carnosine ingestion in humans
Next-generation technologies for multiomics approaches including interactome sequencing
Homogeneously Catalyzed CO 2 Hydrogenation to Formic Acid/Formate with Non‐precious Metal Catalysts
Activation effects of carnosine-and histidine-containing dipeptides on human carbonic anhydrases: a comprehensive study
Degradation of glyoxalase I in Brassica napus stigma leads to self-incompatibility response
Application of 13C-nmr spectroscopy to study the mechanism of N-demethylation of [N Me 13C] codeine by cell-free extracts of Cunninghamella bainieri
The ultimate AGE inhibitors
Vitamins and their derivatives in the prevention and treatment of metabolic syndrome diseases (diabetes),
In vitro and in vivo inhibition of maillard reaction products using amino acids, modified proteins, vitamins, and genistein: A review
Dietary cladode powder from wild type and domesticated Opuntia species reduces atherogenesis in apoE knock-out mice
Naturally occurring variation in the glutathione-S-transferase 4 gene determines neurodegeneration after traumatic brain injury
Chemical Vapor Deposition of Thin‐Film Platinum
Protection from diabetes-induced atherosclerosis and renal disease by D-carnosine-octylester: effects of early vs late inhibition of advanced glycation end …
The electrophile responsive proteome: integrating proteomics and lipidomics with cellular function
Lipid Peroxide-Derived Short-Chain Aldehydes are Involved in Aluminum Toxicity of Wheat (Triticum aestivum) Roots
Carnosine and advanced glycation end products: a systematic review
The Protective Effect of Hydralazine against Hydrogen Peroxide (H2O2)-Induced Oxidative Damage in C6 Glial Cell Line
Inhibiting effects of epigallocatechin gallate (EGCG) on the formation of age pigment in vitro and in vivo
Effects of supplementation with carnosine and other histidine-containing dipeptides on chronic disease risk factors and outcomes: protocol for a systematic review of …
Carnosine activates cellular stress response in podocytes and reduces glycative and lipoperoxidative stress
A carnosine analog with therapeutic potentials in the treatment of disorders related to oxidative stress
Hydroxyalkenals and oxidized phospholipids modulation of endothelial cytoskeleton, focal adhesion and adherens junction proteins in regulating endothelial barrier …
Bioactivation of fluorotelomer alcohols in isolated rat hepatocytes
Hyperglycemia and glycation in diabetic complications
Contribution of oxidative stress to TiO2 nanoparticle-induced toxicity
Carnosine metabolism in diabetes is altered by reactive metabolites
Further elucidation of beer flavor instability: the potential role of cysteine-bound aldehydes
L-carnosine alters some hemorheologic and lipid peroxidation parameters in nephrectomized rats
Inhibitory effect of paeoniflorin on methylglyoxal-mediated oxidative stress in osteoblastic MC3T3-E1 cells
Bioaccessibility of the bioactive peptide carnosine during in vitro digestion of cured beef meat
Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization
Intervention strategies to inhibit protein Carbonylation by lipoxidation‐derived reactive Carbonyls
Food & Function
Urinary Levels of the Acrolein Conjugates of Carnosine Are Associated with Cardiovascular Disease Risk
Carnosine protects pancreatic beta cells and islets against oxidative stress damage
Role of the glyoxalase system in astrocyte-mediated neuroprotection
Carnosine: can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential?
Cytoprotection by almond skin extracts or catechins of hepatocyte cytotoxicity induced by hydroperoxide (oxidative stress model) versus glyoxal or methylglyoxal …
Night Migratory Songbirds Exhibit Metabolic Ability to Support High Aerobic Capacity during Migration
Intrinsic carnosine metabolism in the human kidney
Muscle carnosine in experimental autoimmune encephalomyelitis and multiple sclerosis
Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation
Investigations on the effect of antioxidant type and concentration and model system matrix on acrylamide formation in model Maillard reaction systems
Effect of carnosine supplementation on lipid profile, fasting blood glucose, HbA1C and insulin resistance: A systematic review and meta-analysis of long-term …
Molecular mechanisms of acrolein-mediated myelin destruction in CNS trauma and disease
An update on amine oxidase inhibitors: multifaceted drugs
Effect of melatonin intake on postprandial blood glucose in the breakfast
Lipoxidation in cardiovascular diseases
Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway
Ability of three kind of imidazole dipeptides, carnosine, anserine, and balenine, to interact with unsaturated fatty acid-derived aldehydes and carbohydrate-derived …
Hydralazine Dopaminergic Protects Neurons Nigrostriatal From MPP+ and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway
(+)-Catechin prevents methylglyoxal-induced mitochondrial dysfunction and apoptosis in EA. hy926 cells
Perspectives in Diabetes Role of Oxidative Stress in Diabetic Complications
Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells
GLO1 overexpression in human malignant melanoma
Therapeutic interventions against accumulation of advanced glycation end products (AGEs)
Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases
Cleaving effect of melatonin on crosslinks in advanced glycation end products
Muscle carnosine is associated with cardiometabolic risk factors in humans
Development and validation of a HPLC method for the direct separation of carnosine enantiomers and analogues in dietary supplements
Dermal toxicity and environmental contamination: electron transfer, reactive oxygen species, oxidative stress, cell signaling, and protection by antioxidants
An antioxidant screen identifies candidates for protection of cochlear hair cells from gentamicin toxicity
Homology modeling of human serum carnosinase, a potential medicinal target, and MD simulations of its allosteric activation by citrate
Decreased tumor incidence and increased survival by one year oral low dose arginine supplementation in the mouse
Oral anserine supplementation does not attenuate type-2 diabetes or diabetic nephropathy in BTBR ob/ob mice
Chronic neuroinflammation in Alzheimer’s disease: new perspectives on animal models and promising candidate drugs
Advanced glycation endproducts induce changes in glucose consumption, lactate production, and ATP levels in SH-SY5Y neuroblastoma cells by a redox-sensitive …
Blockade of the formation of insoluble ubiquitinated protein aggregates by EGCG3” Me in the alloxan-induced diabetic kidney
Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity
Actein protects against methylglyoxal‐induced oxidative damage in osteoblastic MC3T3‐E1 cells
Black rice with giant embryo attenuates obesity-associated metabolic disorders in ob/ob mice
Urinary levels of the acrolein conjugates of carnosine are associated with inhaled toxicants
Muscle histidine-containing dipeptides are elevated by glucose intolerance in both rodents and men
The initiation of free radical peroxidation of low-density lipoproteins by glucose and its metabolite methylglyoxal: a common molecular mechanism of vascular wall …
Multifunctional and dual-responsive polymersomes as robust nanocontainers: design, formation by sequential post-conjugations, and pH-controlled drug release
Serum carnosine dipeptidase 1 and ubiquitin C-terminal hydrolase L1 as markers of brain damage in patients after carotid endarterectomy
Antioxidant status, lipid peroxidation and protein oxidation in type 2 diabetic patients; beneficial effects of supplementation with carnosine: A randomized …
Increased Carbonylation , protein aggregation and apoptosis in the spinal cord of mice with experimental autoimmune encephalomyelitis
Cross-link Breakers and Inhibitors
Desensitization of platelet-derived growth factor receptor-β by oxidized lipids in vascular cells and atherosclerotic lesions: prevention by aldehyde Scavengers
Inhibition of Methylglyoxal-Induced Histone H1 Nε-Carboxymethyllysine Formation by (+)-Catechin
The chemistry of aging beer
β-alanyl-L-histidine rescues cognitive deficits caused by feeding a high fat diet in a transgenic mouse model of Alzheimer’s disease
Carnosine: from exercise performance to health
Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBR Ob/Ob mice
Using carboxyfluorescein diacetate succinimidyl ester to monitor intracellular protein glycation
Physiological and therapeutic effects of carnosine on cardiometabolic risk and disease
Ellagic acid inhibits non-enzymatic glycation and prevents proteinuria in diabetic rats
Effect of carnosine supplementation on the plasma lipidome in overweight and obese adults: a pilot randomised controlled trial
Inhibition of tumour cell growth by carnosine: some possible mechanisms
Continuous infusion of phenelzine, cyclosporine A, or their combination: evaluation of mitochondrial bioenergetics, oxidative damage, and cytoskeletal degradation …
Protective effect of orally administered carnosine on bleomycin-induced lung injury
Lipid peroxidation by-products and the metabolic syndrome
Regulation and therapeutic strategies of 4-hydroxy-2-nonenal metabolism in heart disease
Role of glyoxalase 1 in methylglyoxal detoxification–the broad player of psychiatric disorders
Contribution of the HNE-immunohistochemistry to modern pathological concepts of major human diseases
ER stress sensor XBP1 controls anti-tumor immunity by disrupting dendritic cell homeostasis
Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages
L-carnosine and its Derivatives as New Therapeutic Agents for the Prevention and Treatment of Vascular Complications of Diabetes
The cinnamon-derived Michael acceptor cinnamic aldehyde impairs melanoma cell proliferation, invasiveness, and tumor growth
Dietary fatty acids and oxidative stress in the heart mitochondria
Systemic acrolein elevations in mice with experimental autoimmune encephalomyelitis and patients with multiple sclerosis
Antioxidant and cytoprotective properties of high-density lipoproteins in vascular cells
In-Depth AGE and ALE Profiling of Human Albumin in Heart Failure: Ex Vivo Studies
Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE)
Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy
Development of a direct LC-ESI-MS method for the measurement of human serum carnosinase activity
Proteins of the extracellular matrix are sensitizers of photo-oxidative stress in human skin cells
Evaluation of Rubus grandifolius L.(wild blackberries) activities targeting management of type-2 diabetes and obesity using in vitro models
Protective effects of honokiol against methylglyoxal-induced osteoblast damage
Complexes of Copper and Iron with Pyridoxamine, Ascorbic Acid, and a Model Amadori Compound: Exploring Pyridoxamine’s Secondary Antioxidant Activity
Modulation of therapy-induced senescence by reactive lipid aldehydes
Voluntary physical activity counteracts Chronic Heart Failure progression affecting both cardiac function and skeletal muscle in the transgenic Tgαq* 44 mouse model
Plant-derived phenolics inhibit the accrual of structurally characterised protein and lipid oxidative modifications
Inhibitory effects of compounds isolated from roots of Cynanchum wilfordii on oxidation and glycation of human low-density lipoprotein (LDL)
Photochemical processed materials
Effects of bergenin on methylglyoxal‐induced damage in osteoblastic MC3T3‐E1 cells
Protein lipoxidation: detection strategies and challenges
Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms
Functionalised Flouroquinolones as a Potentially Novel Class of Anti-inflammatory and Anti-glycation Compounds; Synthesis and Pharmacological Appraisal
Development and validation of a sensitive LC–MS/MS assay for the quantification of anserine in human plasma and urine and its application to pharmacokinetic study
Pharmacological approaches to the treatment of diabetic complications
Beta cell response to nutrient overload involves phospholipid remodelling and lipid peroxidation
Does supplementation with carnosine improve cardiometabolic health and cognitive function in patients with pre-diabetes and type 2 diabetes? study protocol …
Glabridin alleviates the toxic effects of methylglyoxal on osteoblastic MC3T3-E1 cells by increasing expression of the glyoxalase system and Nrf2/HO-1 signaling and …
Interactions of silica nanoparticles with therapeutics for oxidative stress attenuation in neurons
Healthfulness
Diurnal variations in serum metabolites of wintering redheaded buntings
Cytotoxicity of malondialdehyde and cytoprotective effects of taurine via oxidative stress and PGC-1α signal pathway in C2C12 cells
Protein oxidation in diabetes mellitus
Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice
Hydrogen Sulfide and Carnosine: Modulation of Oxidative Stress and Inflammation in Kidney and Brain Axis
Effect of Oral carnosine supplementation on urinary TGF-β in diabetic nephropathy: a randomized controlled trial
Carnosine supplementation reduces plasma soluble transferrin receptor in healthy overweight or obese individuals: a pilot randomised trial
A study of selective vulnerability to diabetes of nerves supplying the ileum using in vitro models
Role of the glyoxalase system in Alzheimer’s disease
Chicken consumption and insulin resistance in non-diabetic older adults
Cytoprotective effects of xanthohumol against methylglyoxal‐induced cytotoxicity in MC3T3‐E1 osteoblastic cells
Mass spectrometric quantification of amino acid oxidation products identifies oxidative mechanisms of diabetic end-organ damage
Facts about the formation of new antioxidants in natural samples after subcritical water extraction
Plasma carnosine, but not muscle carnosine, attenuates high-fat diet-induced metabolic stress
Magnolol protects pancreatic β-cells against methylglyoxal-induced cellular dysfunction
Beta-alanine supplementation, muscle carnosine and exercise performance
TherapeuTic TargeTing of neuronal MiTochondria in Brain injury
Carnosinase-1 overexpression, but not aerobic exercise training, affects the development of diabetic nephropathy in BTBR ob/ob mice
Limonene attenuates methylglyoxal-induced dysfunction in MC3T3-E1 osteoblastic cells
Analytical methods for the determination of aldehydes
Correlation between serum carnosinase concentration and renal damage in diabetic nephropathy patients
The effects of l-Carnosine on development of metabolic syndrome in rats
Opipramol inhibits lipolysis in human adipocytes without altering glucose uptake and differently from antipsychotic and antidepressant drugs with adverse effects on …
Role of protein kinase C δ in ER stress and apoptosis induced by oxidized LDL in human vascular smooth muscle cells
NADPH oxidase in endothelial cells: impact on atherosclerosis
Role of DDAH-1 in lipid peroxidation product-mediated inhibition of endothelial NO generation
Revisiting traumatic brain injury: from molecular mechanisms to therapeutic interventions
Real-time monitoring of enzyme-assisted animal protein hydrolysis by NMR spectroscopy–An NMR reactomics concept
Polyphenols of Myrica faya inhibit key enzymes linked to type II diabetes and obesity and formation of advanced glycation end-products (in vitro): Potential role in the …
Luteolin alleviates methylglyoxal-induced cytotoxicity in osteoblastic MC3T3-E1 cells
Proteome wide reduction in AGE modification in streptozotocin induced diabetic mice by hydralazine mediated transglycation
Quantification of N2-Carboxymethyl-2′-deoxyguanosine in Calf Thymus DNA and Cultured Human Kidney Epithelial Cells by Capillary High-Performance Liquid …
Sciadopitysin alleviates methylglyoxal-mediated glycation in osteoblastic MC3T3-E1 cells by enhancing glyoxalase system and mitochondrial biogenesis
Hyperglycemia does not affect iron mediated toxicity of cultured endothelial and renal tubular epithelial cells: influence of L-carnosine
Intranasal carnosine attenuates transcriptomic alterations and improves mitochondrial function in the Thy1-aSyn mouse model of Parkinson’s disease
Comparative Cerebroprotective Potential of d-and l-Carnosine Following Ischemic Stroke in Mice
Advanced glycation end products and diabetic complications
Metabolic effects of oral phenelzine treatment on high-sucrose-drinking mice
Urinary Carnosinase-1 Excretion is Associated with Urinary Carnosine Depletion and Risk of Graft Failure in Kidney Transplant Recipients: Results of the …
Aldo-keto reductase family 1, member B10 is secreted through a lysosome-mediated non-classical pathway
Involvement of PPARγ in Alteration of Mechanisms of Autophagy Pathway in Acrolein Toxicity
Low plasma carnosinase activity promotes carnosinemia following carnosine ingestion in humans 2
Omega-3 polyunsaturated lipophenols, how and why?
Evaluation of Carnosine Intervention in the Thy1-aSyn Mouse Model of Parkinson’s Disease
Parkinson’s Disease and Type-2 Diabetes: Methylglyoxal may be a Common Causal Agent; Carnosine could be Protective
Phenelzine: an old drug that may hold clues to the development of new neuroprotective agents
Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell self-renewal, differentiation and survival
Does low serum carnosinase activity favor high-intensity exercise capacity?
Multifunctional scaffolds for assembling cancer-targeting immune stimulators using chemoselective ligations
Pathogenetic aspects of post-surgical adhesions prevention (review of literature)
Monoamine oxidase inhibitors and neuroprotection: a review
Protective effects of piceatannol on methylglyoxal-induced cytotoxicity in MC3T3-E1 osteoblastic cells
The role of human serum carnosinase 1 in diabetic nephropathy
Intracellular pH regulation of skeletal muscle in the milieu of insulin signaling
Methylglyoxal, a highly reactive diCarbonyl compound, in diabetes, its vascular complications, and other age-related diseases
Neuroprotective and anxiolytic potential of green rooibos (Aspalathus linearis) polyphenolic extract
Physiology and pathophysiology of carnosine
Studies on the pathogenesis of chronic kidney disease
Modulation of the liver protein Carbonylome by the combined effect of marine omega-3 PUFAs and grape polyphenols supplementation in rats fed an obesogenic high …
Antioxidant potential of psychotropic drugs: From clinical evidence to in vitro and in vivo assessment and toward a new challenge for in silico molecular design
Use of carnosine in the prevention of cardiometabolic risk factors in overweight and obese individuals: study protocol for a randomised, double-blind placebo …
Desensitization of Platelet-Derived Growth Factor Receptor-ß by Oxidized Lipids in Vascular Cells and Atherosclerotic Lesions
4-hydroxy-nonenal—A bioactive lipid peroxidation product
Antimelanoma activity of the redox dye DCPIP (2, 6-dichlorophenolindophenol) is antagonized by NQO1
Protocol: Use of carnosine in the prevention of cardiometabolic risk factors in overweight and obese individuals: study protocol for a randomised, double-blind …
Carnosine and histidine-containing dipeptides improve dyslipidemia: a systematic review and meta-analysis of randomized controlled trials
The Cost-Effectiveness of Supplemental Carnosine in Type 2 Diabetes
Exercise alters and β-alanine combined with exercise augments histidyl dipeptide levels and scavenges lipid peroxidation products in human skeletal muscle
Synthesis and characterization of 13C labeled carnosine derivatives for isotope dilution mass spectrometry measurements in biological matrices
Aerobic and resistance training do not influence plasma carnosinase content or activity in type 2 diabetes
Fluorescent sensors for the detection of hydrazine in environmental and biological systems: Recent advances and future prospects
CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications
Advanced Glycation Endproducts,(AGEs): Formation, Complication and Pharmacological Evaluation to Its Inhibition
Methylglyoxal and Other AGEs: Good and Bad Dual Role in the Body
Ascorbic Acid Promotes Detoxification and Elimination of 4-Hydroxy-2(E)-nonenal in Human Monocytic THP-1 Cells
Lipid peroxidation in atherosclerotic cardiovascular diseases
L-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor–α levels in patients with type 2 …
Regulatory landscape of AGE-RAGE-oxidative stress axis and its modulation by PPARγ activation in high fructose diet-induced metabolic syndrome
Diabetes, oxidative stress and therapeutic strategies
Obesity in a model of haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy
Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
Histidine in health and disease: metabolism, physiological importance, and use as a supplement
6-Hydroxydopamine: A far from simple neurotoxin
Catecholamine metabolism via monoamine oxidase (MAO) within myocardium of individuals with type 2 diabetes
Manganese, technetium, and rhenium: Annual survey covering the year 1973
Antioxidant thioether core-crosslinked nanoparticles prevent the bilateral spread of secondary injury to protect spatial learning and memory in a controlled cortical …
Photoremovable protecting groups in chemistry and biology: reaction mechanisms and efficacy
Recent progress in the Horner-Wadsworth-Emmons reaction
The MAO inhibitor phenelzine can improve functional outcomes in mice with established clinical signs in experimental autoimmune encephalomyelitis (EAE)
Almond, hazelnut and walnut, three nuts for neuroprotection in Alzheimer’s disease: A neuropharmacological review of their bioactive constituents
CEdG–a glycated DNA adduct linking altered metabolism and genetic instability
Dose-dependent effects of l-carnosine on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats
Toxicity of protein and DNA-AGEs in neurodegenerative diseases (NDDs) with decisive approaches to stop the deadly consequences
Inflammatory Reaction in Neurological Diseases
High doses of catecholamines activate glucose transport in human adipocytes independently from adrenoceptor stimulation or vanadium addition
Hormetic and regulatory effects of lipid peroxidation mediators in pancreatic beta cells
Formation of Nanostructured Assemblies of Light-harvesting Proteins by Photochemical Methods
Lipophilized derivatives of epigallocatechin gallate (EGCG): preparations and bioactivities
Recent developments in clinical trials for the treatment of traumatic brain injury
Effect of mats with “A Distinctive 4-Layer 3-Dimensional Structure” on sleep quality, anti-oxidative and immunological function
Effect of renoprotective amino acids and a dipeptide on disease progression, nutritional status, and blood-serum phosphate concen-tration in cats with chronic …
Department of Computational Biology and Medical Sciences
Soft gelatin capsules (softgels)
The Champagne Route to Avermectins and Milbemycins
Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity
Protein Carbonylation : Emerging Roles in Plant Redox Biology and Future Prospects
Agricultural Center, USA
A TABLE OF CONTENTS
Understanding the Role of Glyoxalase I During Pollen-Pistil Interaction in Brassicaceae
A TABLE OF CONTENTS
Synthesis and biological evaluation of diarylheptanoids as potential antioxidant and anti-inflammatory agents
Neuroprotective effects of cinnamon (cinnamomum verum) via modulation of stress response signaling
Characteristics of selected antioxidative and bioactive compounds in meat and animal origin products
MASS SPECTROMETRIC STRATEGIES FOR THE STUDY OF PLANT EXTRACTS BIOAVAILABILITY, BIOACTIVITY AND MECHANISMS OF ACTION
Carnosine as a Mechanism-based Intervention in the Thy1-aSyn Mouse Model of Parkinson’s Disease: Neurobehavioral, Biochemical, and Bioinformatic Analyses
Oxidative stress in C. elegans: Discovery of a mechanistic role for gamma-ketoaldehyde lipid peroxidation products in the Free Radical Theory of Aging
Clinically proven natural alternatives for treating depression
SERUM CARNOSINASE CONTENT AND ACTIVITY IN TYPE 2 DIABETIC PATIENTS.
Fermentation Process
Association of proteins modulating immune response and insulin clearance during gestation with antenatal complications in patients with gestational or type 2 …
About AGEs
Oxidative stress and cardiovascular risk: obesity, diabetes, smoking, and pollution: part 3 of a 3-part series
Session held on 8 July 2016
Visible Light Photorelease of Carboxylate Anions by Mediated Photoinduced Electron Transfer to Pyridinium-based Protecting Groups
Glucose independent pleiotropic effects of a dipeptidyl peptidase-4 inhibitor on diabetic complications
Vanadium-dependent activation of glucose transport in adipocytes by catecholamines is not mediated via adrenoceptor stimulation or monoamine oxidase …
Effect of Carnosine or β-Alanine Supplementation on Markers of Glycemic Control and Insulin Resistance in Humans and Animals: A Systematic Review and Meta …
Mass spectrometric study of genetic and epigenetic DNA modifications
Maillard reaction and antioxidative effect of dry honey in turkey meat system
Protein engineering for novel protein-protein interactions and protein labeling
Identification of cathepsin B and L as novel UVA targets upstream of cutaneous lysosomal-autophagic dysregulation
Poster session 1
The effects of the trapping of methylglyoxal by flavonoids on antioxidant and antibacterial activity
Antioxidant Nanoparticles as Delivery Systems
Deficient aldehyde detoxification in the nigrostriatal pathway: A potential animal model for Parkinson’s disease
Fluorescent photolabile protecting groups based on O and N heterocycles
Development of the engineered biological model systems and chemoselective redox responsive ligation (CRRL)
Oligomérisation sélective de l’éthylène avec des complexes de chrome: étude théorique et expérimentale combinée-et extensions à d’autres métaux
Google-16 is logged in
Quinolones as potential anti HIV-1 agents targeted at Tat/TAR recognition
Neurochemical and neuroprotective aspects of phenelzine and its active metabolite B-phenylethylidenehydrazine
Diabetic nephropathy: pathology, genetics and carnosine metabolism
Water soluble vitamins: clinical research and future application
Carnosine, a therapeutic potential for critical limb ischemic.
Immunomodulation mechanism of antidepressants: interactions between serotonin/norepinephrine balance and Th1/Th2 balance
Multifunctional and Stimuli-Responsive Polymersomes for Biomedical Applications
Dendronized Polymers with Tailored Intermolecular Interactions: Synthesis and Thermomechanical Characterization
Genetics in experimental traumatic brain injury
Analytical studies on the N-dealkylation of drug molecules by Cunninghamella sp.
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